fruR [2019-09-03 11:12:57]

transcription repressor of the fruR-fruK-fruA operon, DeoR family

locus: BSU_14380

pI: 5.68

mw: 27.67 kDa

protein length: 251 aa

gene length: 756 bp

function: regulation of fructose utilization

product: transcription repressor

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.7|Utilization of fructose]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]

Gene

Coordinates: 1,507,578 1,508,333

Expression and Regulation

Operons

• genes: [gene|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]-[gene|502AA809C8C95F8886DD91FBB7DDBECC63342327|fruK]-[gene|973C3D3FBFDCA095A760C5F49A96D8BE48771014|fruA]
  description: [pubmed|22383849]

  regulatory mechanism

  • [protein|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|FruR]: repression, (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS]), in [regulon|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|FruR regulon]

  regulation

  • induced in the presence of fructose ([protein|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|FruR]) (according to [http://dbtbs.hgc.jp/COG/prom/fruRKA.html DBTBS])

Biological materials

Mutant

• BKE14380 ([gene|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE14380 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCTTCACCTCCTAATGA, downstream forward: _UP4_ACTGTCGTAAAGGTAGTGAA
• BKK14380 ([gene|7FD2294B0538EB6D83DC3E0752600D2464CDE4A3|fruR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK14380 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCTTCACCTCCTAATGA, downstream forward: _UP4_ACTGTCGTAAAGGTAGTGAA

References

• 14651647,10627040